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Proven Technology Enhances Breast Cancer Detection, Improves Accuracy

Health recently announced that they have added the latest development in the
fight against breast cancer – iCAD’s Profound AI for digital breast
tomosyntheses (DBT), also known as 3D mammography – to their Mammography
Program. ProFound AI for DBT was the first artificial intelligence (AI)
software for DBT to be FDA-cleared.

DBT, also called
three-dimensional (3-D) mammography, is an advanced form of breast imaging, or mammography,
that uses a low-dose x-ray system and computer reconstructions to create
three-dimensional images of the breasts. Navicent Health was one of the first
health systems in the state to adopt DBT in 2016 and has since been able to
provide more accurate images for the early detection and treatment of breast


Unlike traditional two-dimensional
mammograms, DBT sweeps in a slight arc over the breast, taking hundreds of images
of the breast tissue. A computer then uses these images to produce a layered 3D
image of the breast tissue. This 3D image provides greater detail and allows
the radiologist to see within the breast layer by layer to find cancer cells earlier
than ever before.


While DBT provides more information
for clinicians compared to 2D mammography, the vast number of images can be complex
for radiologists to read. By introducing Profound AI, Navicent Health is
addressing the complexities of reading 3D mammography exams.


Trained with one of the largest
available DBT datasets, ProFound AI rapidly and accurately analyzes each DBT
image, or slice, and provides radiologists with key information that assists in
clinical decision-making and improving reading efficiency. Clinical data from a
large reader study showed ProFound AI for DBT improved radiologist sensitivity
by eight percent, reduced the rate of false positives and unnecessary patient
recalls by 7.2 percent, and slashed reading time for radiologists by 52.7

3D mammogram performed at Navicent Health is now processed with Profound AI,
providing improved analysis and allowing radiologists to read exams more
efficiently and consistently.

“The integration of
Profound AI into our mammography program offers our patients the best chance at
early detection and treatment of breast cancer. Streamlining and standardizing
the analysis of a study with Profound AI ultimately ensures greater care for
our patients,” says Tom Oliver, MD, President of Hospitals and Clinics for
Navicent Health.

Tom Oliver, MD

“Navicent Health is
one of iCAD’s ‘Centers of Excellence,’ as the facility also offers breast
intraoperative radiation therapy (IORT) with iCAD’s Xoft® Axxent®
Electronic Brachytherapy (eBx®) System®,” says Michael Klein,
Chairman and CEO of iCAD. “ProFound AI is clinically proven to help clinicians
detect cancers sooner, when they may be more easily treated; the Xoft System
offers a one-day treatment option that allows select early-stage breast cancer
patients to replace weeks of daily radiation with one targeted dose of
radiation, delivered at the time of surgery. Paired together, ProFound AI and
Xoft are powerful solutions in the fight against breast cancer that can help women
transition from ‘cancer discovery’ to ‘cancer recovery’ more swiftly, with
fewer side effects and overall improved quality of life.”



[i] Conant, E. et al. (2019). Improving Accuracy and
Efficiency with Concurrent Use of Artificial Intelligence for Digital Breast
Tomosynthesis. Radiology: Artificial Intelligence. 1 (4). Accessed via